Hangover is a terrible thing if a person gets over in the morning after the last night booze party. If a person is having a severe headache and dryness in mouth along with nauseating feeling then it must be a Hangover for sure. The main causes of Hangover may not be still known but research is going on what are the exact reasons for causing the hangover. In hangover the person suffers from extreme dryness in mouth, severe headache and dizziness with nauseating feeling. This makes a person feels sick and repulsive over the taste of alcohol. In the recent study it has been found that acetaldehyde which is the first product of alcohol metabolism can lead to hangover for a particular type of genotype in alcohol drinkers.

How Acetaldehyde increase in Hangover

It has been found in the latest research that Acetaldehyde can be a culprit for getting hangovers in the morning. The product that comes out from metabolism of alcohol is more toxic than the alcohol itself. This is caused by the alcohol which is broken down in the liver by an enzyme in the body called as Acetaldehyde dehydrogenase. Other enzyme in the body called gluetathione along with acetaldehyde produces the non toxic acetate. But this happens only if short amount of alcohol is consumed in the body. If the alcohol consumed by a person exceeds the glutathione in the body then it causes acetaldehyde to build up in the body. Due to this the blocked acetaldehyde breaks down into a substance which is not only toxic but also causes a person severe vomiting and headache. The intensity of this is so bad that the person becomes repulsive to the alcohol even to the though of alcohol or to the taste of alcohol. This withdrawal symptom is more severe in case of women as women already have fewer amounts of acetaldehyde dehydrogenase and glutathione in their body making them more prone to hangovers. The most common symptoms of hangovers like fatigue, stomach irritation and illness can be aroused by further phenomenon called glutathione rebound.

Alcohol and Cell damage

Researchers also noticed that due to presence of excess of acetaldehyde in the body causes damage to the liver cells and it is not only because of alcohol. Now research is more stressed towards finding cure for the effects of acetaldehyde.